Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases.

نویسندگان

  • Dean D Metcalfe
  • Ruby Pawankar
  • Steven J Ackerman
  • Cem Akin
  • Frederic Clayton
  • Franco H Falcone
  • Gerald J Gleich
  • Anne-Marie Irani
  • Mats W Johansson
  • Amy D Klion
  • Kristin M Leiferman
  • Francesca Levi-Schaffer
  • Gunnar Nilsson
  • Yoshimichi Okayama
  • Calman Prussin
  • John T Schroeder
  • Lawrence B Schwartz
  • Hans-Uwe Simon
  • Andrew F Walls
  • Massimo Triggiani
چکیده

Biomarkers of disease activity have come into wide use in the study of mechanisms of human disease and in clinical medicine to both diagnose and predict disease course; as well as to monitor response to therapeutic intervention. Here we review biomarkers of the involvement of mast cells, basophils, and eosinophils in human allergic inflammation. Included are surface markers of cell activation as well as specific products of these inflammatory cells that implicate specific cell types in the inflammatory process and are of possible value in clinical research as well as within decisions made in the practice of allergy-immunology.

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عنوان ژورنال:
  • The World Allergy Organization journal

دوره 9  شماره 

صفحات  -

تاریخ انتشار 2016